Antihistamine

Benadryl Dosage for Dogs

Calculate the safe Benadryl (Diphenhydramine HCL) dose for your dog based on weight. Adjust the slider below for instant results.

Quick Calculator

lbs
1 lb200 lbs

About Benadryl for Dogs

Benadryl (generic name: Diphenhydramine HCL) is an over-the-counter medication in the Antihistamine category. It is commonly used for dogs to treat:

  • Allergic reactions
  • Itchiness
  • Mild sedation
  • Insect stings
  • Hives

Dosing Notes

1 mg per pound of body weight. Liquid: 1 ml per 2.5 lbs.

Warnings & Contraindications

Warnings

  • Use only plain diphenhydramine — avoid combination products with decongestants or pain relievers
  • May cause drowsiness, dry mouth, or urinary retention

Do NOT Use If

  • Do not use in pets with glaucoma, high blood pressure, or cardiovascular disease without vet approval

Important Notes

  • Always verify the product contains ONLY diphenhydramine as the active ingredient

Benadryl Dosage Chart for Dogs

WeightDose (mg)Frequency
5 lbs5 mgEvery 8 hours as needed
10 lbs10 mgEvery 8 hours as needed
20 lbs20 mgEvery 8 hours as needed
30 lbs30 mgEvery 8 hours as needed
40 lbs40 mgEvery 8 hours as needed
50 lbs50 mgEvery 8 hours as needed
60 lbs60 mgEvery 8 hours as needed
80 lbs80 mgEvery 8 hours as needed
100 lbs100 mgEvery 8 hours as needed

40 lb Dog

Benadryl Dose

Generally safe for dogs at this dose

40mg

💊

Tablet Form

1.5 × 25 mg tablets

💧

Liquid Form

16.0 ml (3.2 tsp)

🕐

Frequency

Every 8 hours as needed

Full Dose Calculator

All 8 medications in one tool

Always consult your veterinarian before giving any medication to your pet. These dosages are general guidelines. Individual pets may require different dosing.

Other Medication Calculators